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Contribution of a neuroscience-informed approach for developing interventions for acute stress reaction
  1. Charles Verdonk1,2,
  2. L Giaume3 and
  3. M Trousselard4,5
  1. 1Laureate Institute for Brain Research, Tulsa, Oklahoma, USA
  2. 2VIFASOM (EA 7330 Vigilance Fatigue, Sommeil et Santé Publique), Université de Paris, Paris, France
  3. 3Paris Fire Brigade, Paris, France
  4. 4French Armed Forces Biomedical Research Institute, Bretigny-sur-Orge, France
  5. 5French Military Health Service Academy, Paris, France
  1. Correspondence to Dr Charles Verdonk, Laureate Institute for Brain Research, Tulsa, OK 74136-3326, USA; cverdonk{at}

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We commend the experts from five armed forces for their article on the recent development of a peer-based intervention to manage acute stress reaction (ASR) in service members during military operations.1 The intervention consists of five sequential actions implemented by teammates on the affected individual, aiming to restore cognitive control over neurocognitive perturbations associated with acute stress.2 In their paper, the experts emphasised the need for further research to understand when the intervention is effective, and assess its impact on short-term and long-term recovery trajectories.1 Beyond this, we advocate for the development of a mechanistic, neuroscience-informed approach to characterise how the proposed intervention works. Combining the efforts from effectiveness research and basic science has the potential to advance the field in several ways. First, …

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  • Contributors CV drafted the original version of the manuscript. LG and MT edited the original version of the manuscript. CV, LG and MT equally contributed to the final edits with submission being managed by CV. All authors have read and approved the final manuscript before submission.

  • Funding The authors have not declared a specific grant for this research from any funding agency in the public, commercial or not-for-profit sectors.

  • Disclaimer The opinions or assertions expressed here are the private views of the authors and are not to be considered as official or as reflecting the views of the French Military Health Service and the Laureate Institute for Brain Research.

  • Competing interests None declared.

  • Provenance and peer review Not commissioned; internally peer reviewed.