RT Journal Article
SR Electronic
T1 Retrospective analysis of tranexamic acid administration in French war-wounded between October 2016 and September 2020
JF BMJ Military Health
JO BMJ Mil Health
FD British Medical Journal Publishing Group
SP e002321
DO 10.1136/military-2022-002321
A1 Thibault Pinna
A1 N Py
A1 L Aigle
A1 S Travers
A1 P Pasquier
A1 N Cazes
YR 2023
UL http://militaryhealth.bmj.com/content/early/2023/02/13/military-2022-002321.abstract
AB Introduction Since 2013, the French Army Health Service, in agreement with international experts, has recommended the administration of 1 g of tranexamic acid (TXA) in trauma patients in haemorrhagic shock or at risk of bleeding within 3 hours of the trauma.Methods The aim of this analysis was to describe the administration of TXA in French military personnel wounded during military operations in the Sahelo-Sahelian band between October 2016 and September 2020. Data were collected from forward health records and hospital data from the French hospital where the casualty was finally evacuated. Underuse of TXA was defined as the lack of administration in casualties who had received a blood transfusion with one or more of red blood cells, low-titre whole blood or French lyophilised plasma within the first 24 hours of injury and overuse as its administration in the non-transfused casualty.Results Of the 76 patients included, 75 were men with an average age of 28 years. Five patients died during their management. 19 patients received TXA (25%) and 16 patients were transfused (21%). Underuse of TXA occurred in 3 of the 16 patients (18.8%) transfused. Overuse occurred in 6 of 60 (10%) non-transfused patients.Conclusion The analysis found an important underuse of TXA (almost 20%) and highlighted the need for optimising the prehospital clinical practice guidelines to aid prehospital medical practitioners more accurately in administering TXA to casualties that will require blood products.No data are available.