pH | Anion gap | Glucose | Osmolar gap | Contribution to osmolar gap* | |
---|---|---|---|---|---|
Ethanol | N | N | N | High | (Ethanol)/3.8 |
Isopropanolol | N | N | N | High | (Isopropanolol)/6.0 |
Methanol | Low | High | N/high | High | (Methanol)/3.2 |
Ethylene glycol | Low | High | N | High | (Ethylene glycol)/6.2 |
*The contribution to the osmolar gap is estimated by taking the plasma concentration of the alcohol (mg/dL) and dividing by the number indicated. For example, a serum ethanol concentration of 80 mg/dL will contribute 21 to the osmolar gap (as 80 mg/dL divided by 3.8=21). The metabolites of some alcohols also contribute to the osmolar gap and are unmeasured.17