Elsevier

Journal of Affective Disorders

Volume 275, 1 October 2020, Pages 145-148
Journal of Affective Disorders

Short communication
Prevalence of depression and its association with quality of life in clinically stable patients with COVID-19

https://doi.org/10.1016/j.jad.2020.06.033Get rights and content

Highlights

  • Patients infected with COVID-19 are vulnerable to mental health problems.

  • The prevalence of depression was 43.1% (95%CI: 39.6%−46.6%) in clinically stable patients with COVID-19. Patients with depression had lower QOL than those without.

  • Regular screening and appropriate treatment of depression are warranted for patients with COVID-19.

Abstract

Introduction

High risk of mental health problems is associated with Coronavirus Disease 2019 (COVID-19). This study explored the prevalence of depressive symptoms (depression hereafter) and its relationship with quality of life (QOL) in clinically stable patients with COVID-19.

Methods

This was an online survey conducted in COVID-19 patients across five designated isolation hospitals for COVID-19 in Hubei province, China. Depression and QOL were assessed with standardized instruments.

Results

A total of 770 participants were included. The prevalence of depression was 43.1% (95%CI: 39.6%-46.6%). Binary logistic regression analysis found that having a family member infected with COVID-19 (OR=1.51, P= 0.01), suffering from severe COVID-19 infection (OR=1.67, P= 0.03), male gender (OR=0.53, P<0.01), and frequent social media use to obtain COVID-19 related information (OR=0.65, P<0.01) were independently associated with depression. Patients with depression had lower QOL than those without.

Conclusion

Depression is highly prevalent in clinically stable patients with COVID-19. Regular screening and appropriate treatment of depression are urgently warranted for this population.

Keywords

Depression
Quality of life
COVID-19
Stable

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1

These authors contributed equally to this work.

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