A new hemostatic agent: initial life-saving experience with Celox (chitosan) in cardiothoracic surgery

Ann Thorac Surg. 2009 Feb;87(2):e13-4. doi: 10.1016/j.athoracsur.2008.09.046.

Abstract

Celox (MedTrade Products Ltd, Cheshire, UK) is a proprietary preparation of chitosan, indicated for moderate to severe hemorrhage and currently used for hemostasis in the emergency and military settings. We describe its lifesaving use in 2 patients undergoing cardiothoracic surgery in which conventional techniques had failed.

Publication types

  • Case Reports

MeSH terms

  • Blood Loss, Surgical / prevention & control
  • Chitosan / administration & dosage*
  • Coronary Artery Bypass / adverse effects
  • Coronary Artery Bypass / methods
  • Follow-Up Studies
  • Hemostatics / therapeutic use*
  • Humans
  • Male
  • Middle Aged
  • Postoperative Hemorrhage / diagnosis
  • Postoperative Hemorrhage / therapy*
  • Risk Assessment
  • Sensitivity and Specificity
  • Thoracotomy / adverse effects*
  • Thoracotomy / methods
  • Treatment Outcome
  • Wounds, Penetrating / diagnosis
  • Wounds, Penetrating / therapy

Substances

  • Hemostatics
  • Chitosan