User profiles for "author:A Parini"
Angelo PariniINSERM Verified email at inserm.fr Cited by 8858 |
Monoamine oxidases as sources of oxidants in the heart
…, J Mialet-Perez, N Paolocci, A Parini… - Journal of molecular and …, 2014 - Elsevier
Oxidative stress can be generated at several sites within the mitochondria. Among these,
monoamine oxidase (MAO) has been described as a prominent source. MAOs are …
monoamine oxidase (MAO) has been described as a prominent source. MAOs are …
[HTML][HTML] Revisiting the hallmarks of aging to identify markers of biological age
The Geroscience aims at a better understanding of the biological processes of aging, to
prevent and/or delay the onset of chronic diseases and disability as well as to reduce the …
prevent and/or delay the onset of chronic diseases and disability as well as to reduce the …
[HTML][HTML] Monoamine oxidases, oxidative stress, and altered mitochondrial dynamics in cardiac ageing
…, DE Edmondson, A Mattevi, A Parini… - … medicine and cellular …, 2017 - hindawi.com
The advances in healthcare over the past several decades have resulted in populations now
living longer. With this increase in longevity, a wider prevalence of cardiovascular diseases …
living longer. With this increase in longevity, a wider prevalence of cardiovascular diseases …
Length‐independent telomere damage drives post‐mitotic cardiomyocyte senescence
…, A Owens, LC Greaves, KL Kolsky, A Parini… - The EMBO …, 2019 - embopress.org
Ageing is the biggest risk factor for cardiovascular disease. Cellular senescence, a process
driven in part by telomere shortening, has been implicated in age‐related tissue dysfunction …
driven in part by telomere shortening, has been implicated in age‐related tissue dysfunction …
Mesenchymal stem cells promote matrix metalloproteinase secretion by cardiac fibroblasts and reduce cardiac ventricular fibrosis after myocardial infarction
…, N Auge, AN Salvayre, P Bourin, A Parini… - Stem …, 2009 - academic.oup.com
Recent studies showed that mesenchymal stem cells (MSCs) transplantation significantly
decreased cardiac fibrosis; however, the mechanisms involved in these effects are still …
decreased cardiac fibrosis; however, the mechanisms involved in these effects are still …
Oxidative stress by monoamine oxidase mediates receptor-independent cardiomyocyte apoptosis by serotonin and postischemic myocardial injury
Background—Serotonin (5-hydroxytryptamine [5-HT]), released by activated platelets during
cardiac ischemia, is metabolized by the mitochondrial enzyme monoamine oxidase A (MAO …
cardiac ischemia, is metabolized by the mitochondrial enzyme monoamine oxidase A (MAO …
CD4+ T Cells Promote the Transition From Hypertrophy to Heart Failure During Chronic Pressure Overload
…, C Vinel, C Delage, D Calise, M Dutaur, A Parini… - Circulation, 2014 - Am Heart Assoc
Background—The mechanisms by which the heart adapts to chronic pressure overload,
producing compensated hypertrophy and eventually heart failure (HF), are still not well …
producing compensated hypertrophy and eventually heart failure (HF), are still not well …
Oxidative stress–dependent sphingosine kinase-1 inhibition mediates monoamine oxidase A–associated cardiac cell apoptosis
…, MH Seguelas, N Leducq, I Seif, A Parini… - Circulation …, 2007 - Am Heart Assoc
The mitochondrial enzyme monoamine oxidase (MAO), its isoform MAO-A, plays a major
role in reactive oxygen species–dependent cardiomyocyte apoptosis and postischemic …
role in reactive oxygen species–dependent cardiomyocyte apoptosis and postischemic …
Intracoronary autologous mononucleated bone marrow cell infusion for acute myocardial infarction: results of the randomized multicenter BONAMI trial
Aims Intracoronary administration of autologous bone marrow cells (BMCs) leads to a
modest improvement in cardiac function, but the effect on myocardial viability is unknown …
modest improvement in cardiac function, but the effect on myocardial viability is unknown …
Ex vivo pretreatment with melatonin improves survival, proangiogenic/mitogenic activity, and efficiency of mesenchymal stem cells injected into ischemic kidney
…, L Daniel, P Bianchi, D Calise, P Bourin, A Parini… - Stem …, 2008 - academic.oup.com
Bone marrow mesenchymal stem cells (MSCs) have shown great potential in cell therapy of
solid organs. Approaches to improving the ability of grafted MSCs to survive and secrete …
solid organs. Approaches to improving the ability of grafted MSCs to survive and secrete …