User profiles for "author:C D Young"

Chadwin D. Young

University of Texas at Dallas
Verified email at utdallas.edu
Cited by 5539

[HTML][HTML] Sugar and fat–that's where it's at: metabolic changes in tumors

CD Young, SM Anderson - Breast Cancer Research, 2008 - Springer
Tumor cells exhibit an altered metabolism, characterized by increased glucose uptake and
elevated glycolysis, which was first recognized by Otto Warburg 70 years ago. Warburg …

[HTML][HTML] Transforming growth factor-β signaling in fibrotic diseases and cancer-associated fibroblasts

X Shi, CD Young, H Zhou, XJ Wang - Biomolecules, 2020 - mdpi.com
Transforming growth factor-β (TGF-β) signaling is essential in embryo development and
maintaining normal homeostasis. Extensive evidence shows that TGF-β activation acts on …

Molecular profiling of the residual disease of triple-negative breast cancers after neoadjuvant chemotherapy identifies actionable therapeutic targets

JM Balko, JM Giltnane, K Wang, LJ Schwarz… - Cancer discovery, 2014 - AACR
Neoadjuvant chemotherapy (NAC) induces a pathologic complete response (pCR) in
approximately 30% of patients with triple-negative breast cancers (TNBC). In patients …

Large ferroelectric polarization of TiN/Hf0. 5Zr0. 5O2/TiN capacitors due to stress-induced crystallization at low thermal budget

SJ Kim, D Narayan, JG Lee, J Mohan, JS Lee… - Applied Physics …, 2017 - pubs.aip.org
We report on atomic layer deposited Hf 0.5 Zr 0.5 O 2 (HZO)-based capacitors which exhibit
excellent ferroelectric (FE) characteristics featuring a large switching polarization (45 μC/cm …

Cosponsorship in the US Congress

RK Wilson, CD Young - Legislative Studies Quarterly, 1997 - JSTOR
Over half of all bills introduced in the US Congress are cosponsored, and, while many
observers assume that cosponsorship is crucial to the legislative process, few have …

[PDF][PDF] Climate change and food security: risks and responses

V Gitz, A Meybeck, L Lipper, CD Young… - Food and Agriculture …, 2016 - ciheam.org
Climate change threatens to reverse the progress made so far in the fight against hunger
and malnutrition. As highlighted by the latest assessment report of the Intergovernmental …

Mutant PIK3CA accelerates HER2-driven transgenic mammary tumors and induces resistance to combinations of anti-HER2 therapies

AB Hanker, AD Pfefferle, JM Balko… - Proceedings of the …, 2013 - National Acad Sciences
Human epidermal growth factor receptor 2 (HER2; ERBB2) amplification and
phosphatidylinositol-4, 5-bisphosphate 3-kinase, catalytic subunit alpha (PIK3CA) mutations …

[HTML][HTML] Modulation of glucose transporter 1 (GLUT1) expression levels alters mouse mammary tumor cell growth in vitro and in vivo

CD Young, AS Lewis, MC Rudolph, MD Ruehle… - PloS one, 2011 - journals.plos.org
Tumor cells exhibit an altered metabolism characterized by elevated aerobic glycolysis and
lactate secretion which is supported by an increase in glucose transport and consumption …

Dipole model explaining high-k/metal gate field effect transistor threshold voltage tuning

PD Kirsch, P Sivasubramani, J Huang… - Applied Physics …, 2008 - pubs.aip.org
An interface dipole model explaining threshold voltage (V t) tuning in HfSiON gated n-
channel field effect transistors (n FETs) is proposed. V t tuning depends on rare earth (RE) …

Novel nicotinic action of the sulfoximine insecticide sulfoxaflor

GB Watson, MR Loso, JM Babcock, JM Hasler… - Insect biochemistry and …, 2011 - Elsevier
The novel sulfoximine insecticide sulfoxaflor is as potent or more effective than the
neonicotinoids for toxicity to green peach aphids (GPA, Myzus persicae). The action of …