User profiles for "author:G P Howell"
Gareth P. HowellAssociate Principal Scientist, AstraZeneca Verified email at astrazeneca.com Cited by 855 |
Copper‐Catalyzed Borylative Couplings with C− N Electrophiles
FJT Talbot, Q Dherbassy, S Manna, C Shi… - Angewandte …, 2020 - Wiley Online Library
Copper‐catalyzed borylative multicomponent reactions (MCRs) involving olefins and C− N
electrophiles are a powerful tool to rapidly build up molecular complexity. The products from …
electrophiles are a powerful tool to rapidly build up molecular complexity. The products from …
Asymmetric and diastereoselective conjugate addition reactions: C–C bond formation at large scale
GP Howell - Organic Process Research & Development, 2012 - ACS Publications
Asymmetric and diastereoselective conjugate addition reactions are discussed from an
industrial perspective including examples of (1) Lewis acid/Brønsted base catalysis,(2) …
industrial perspective including examples of (1) Lewis acid/Brønsted base catalysis,(2) …
Catalytic asymmetric synthesis of acyclic arrays by tandem 1, 4-addition-aldol reactions
GP Howell, SP Fletcher, K Geurts… - Journal of the …, 2006 - ACS Publications
Herein, we report efficient acyclic stereocontrol in tandem 1, 4-addition-aldol reactions
triggered by catalytic asymmetric organometallic addition. Grignard reagents add to α, β …
triggered by catalytic asymmetric organometallic addition. Grignard reagents add to α, β …
De-Dopplerization and acoustic imaging of aircraft flyover noise measurements
GP Howell, AJ Bradley, MA McCormick… - Journal of Sound and …, 1986 - Elsevier
The technique described in this paper eliminates the Doppler effect from aircraft flyover
noise measurements and generates narrow band spectra at required angles. Such a …
noise measurements and generates narrow band spectra at required angles. Such a …
Nonlinear propagation of aircraft noise in the atmosphere
CL Morfey, GP Howell - AIAA Journal, 1981 - arc.aiaa.org
Nonlinear Propagation of Aircraft Noise in the Atmosphere Page 1 986 AIAA JOURNAL VOL. 19,
NO. 8 AIAA 80-1041R Nonlinear Propagation of Aircraft Noise in the Atmosphere CL Morfey …
NO. 8 AIAA 80-1041R Nonlinear Propagation of Aircraft Noise in the Atmosphere CL Morfey …
An asymmetric nitro-Mannich reaction applicable to alkyl, aryl, and heterocyclic imines
JC Anderson, GP Howell, RM Lawrence… - The Journal of Organic …, 2005 - ACS Publications
A protocol for the enantioselective nitro-Mannich coupling between alkyl, aryl, and
heterocyclic p-methoxybenzylimines and trimethylsilylnitropropanate catalyzed by a chiral t …
heterocyclic p-methoxybenzylimines and trimethylsilylnitropropanate catalyzed by a chiral t …
Nephron‐sparing surgery across a nation–outcomes from the British Association of Urological Surgeons 2012 national partial nephrectomy audit
A Fernando, S Fowler, T O'Brien… - BJU …, 2016 - Wiley Online Library
Objective To determine the scope and outcomes of nephron‐sparing surgery (NSS), ie
partial nephrectomy, across the UK and in so doing set a realistic benchmark and identify …
partial nephrectomy, across the UK and in so doing set a realistic benchmark and identify …
Copper-catalyzed borylative multicomponent synthesis of quaternary α-amino esters
Copper-catalyzed coupling of readily available ketiminoesters, allenes, and a diboron
affords densely functionalized quaternary α-amino esters bearing adjacent stereocenters …
affords densely functionalized quaternary α-amino esters bearing adjacent stereocenters …
Asymmetric allylation of aryl aldehydes: studies on the scope and mechanism of the palladium catalysed diethylzinc mediated umpolung using phosphoramidite …
GP Howell, AJ Minnaard, BL Feringa - Organic & Biomolecular …, 2006 - pubs.rsc.org
Using modular, monodentate phosphoramidite ligands, enantioselective palladium
catalysed diethylzinc mediated allylation of aldehydes was achieved. The scope of the …
catalysed diethylzinc mediated allylation of aldehydes was achieved. The scope of the …
Cumulative complexity meta-metrics as an efficiency measure and predictor of process mass intensity (PMI) during synthetic route design
L Angelini, CE Coomber, GP Howell, G Karageorgis… - Green …, 2023 - pubs.rsc.org
Functioning as a surrogate for step count, a cumulative complexity meta-metric (∑ CM*),
calculated along the longest linear sequence of a synthetic route, is demonstrated to be a …
calculated along the longest linear sequence of a synthetic route, is demonstrated to be a …