User profiles for "author:J Doherty"

Jen Doherty

Huntsman Cancer Institute
Verified email at dartmouth.edu
Cited by 22273

[HTML][HTML] Type I and II endometrial cancers: have they different risk factors?

…, JL Freudenheim, J Doherty… - Journal of Clinical …, 2013 - ncbi.nlm.nih.gov
Purpose Endometrial cancers have long been divided into estrogen-dependent type I and
the less common clinically aggressive estrogen-independent type II. Little is known about …

[HTML][HTML] Targeting lactate metabolism for cancer therapeutics

JR Doherty, JL Cleveland - The Journal of clinical …, 2013 - Am Soc Clin Investig
Lactate, once considered a waste product of glycolysis, has emerged as a critical regulator
of cancer development, maintenance, and metastasis. Indeed, tumor lactate levels correlate …

ACCF/AHA/ASE/ASNC/HFSA/HRS/SCAI/SCCT/SCMR/STS 2013 multimodality appropriate use criteria for the detection and risk assessment of stable ischemic heart …

MJ Wolk, SR Bailey, JU Doherty, PS Douglas… - Journal of the American …, 2014 - jacc.org
Abstract............. 382 Preface............. 382 1 Introduction............. 383 2 Methods............. 383
Indication Development............. 383 Rating Process and Scoring............. 383 3 …

[HTML][HTML] A comparison of enalapril with hydralazine–isosorbide dinitrate in the treatment of chronic congestive heart failure

…, S Goldman, RD Fletcher, J Doherty… - … England Journal of …, 1991 - Mass Medical Soc
Abstract Background and Methods. To define better the efficacy of vasodilator therapy in the
treatment of chronic congestive heart failure, we compared the effects of hydralazine and …

Protective effects of aspirin against acute myocardial infarction and death in men with unstable angina: results of a Veterans Administration Cooperative Study

HD Lewis Jr, JW Davis, DG Archibald… - … England Journal of …, 1983 - Mass Medical Soc
We conducted a multicenter, double-blind, placebo-controlled randomized trial of aspirin
treatment (324 mg in buffered solution daily) for 12 weeks in 1266 men with unstable angina …

EGF receptor gene mutations are common in lung cancers from “never smokers” and are associated with sensitivity of tumors to gefitinib and erlotinib

…, V Miller, M Zakowski, J Doherty… - Proceedings of the …, 2004 - National Acad Sciences
Somatic mutations in the tyrosine kinase (TK) domain of the epidermal growth factor receptor
(EGFR) gene are reportedly associated with sensitivity of lung cancers to gefitinib (Iressa) …

A human natural killer cell subset provides an innate source of IL-22 for mucosal immunity

M Cella, A Fuchs, W Vermi, F Facchetti, K Otero… - Nature, 2009 - nature.com
Natural killer (NK) cells are classically viewed as lymphocytes that provide innate
surveillance against virally infected cells and tumour cells through the release of cytolytic …

Quantitative evaluation of Escherichia coli host strains for tolerance to cytosine methylation in plasmid and phage recombinants

DM Woodcock, PJ Crowther, J Doherty… - Nucleic acids …, 1989 - academic.oup.com
Many strains of E. coli K12 restrict DNA containing cytosine methylation such as that present
in plant and animal genomes. Such restriction can severely inhibit the efficiency of cloning …

[HTML][HTML] Association between endometriosis and risk of histological subtypes of ovarian cancer: a pooled analysis of case–control studies

CL Pearce, C Templeman, MA Rossing, A Lee… - The lancet …, 2012 - thelancet.com
Background Endometriosis is a risk factor for epithelial ovarian cancer; however, whether
this risk extends to all invasive histological subtypes or borderline tumours is not clear. We …

Activated macrophages are an adaptive element of the colonic epithelial progenitor niche necessary for regenerative responses to injury

SL Pull, JM Doherty, JC Mills… - Proceedings of the …, 2005 - National Acad Sciences
We have identified cellular and molecular features of the stem cell niche required for marked
amplification of mouse colonic epithelial progenitors (ColEPs) that occurs in response to …